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Pranlukast hemihydrate

CAT: 0957-E6047-250mgSize: 250 mgDry Ice: NoHazardous: No
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CAT#:0957-E6047-250mgSize:250 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
150821-03-7
Synonyms
ONO-1078 hemihydrate
Target
Immunology & Inflammation related
Applications
Immunology & Inflammation
Molecular Formula
C27H23N5O4.1/2H2O
Additionnal Information
Pranlukast hemihydrate (ONO-1078 hemihydrate) is an antagonist of cysteinyl leukotriene receptor-1 (CysLT1) that blocks leukotrienes such as LTC4, LTD4, and LTE4, reducing bronchoconstriction and airway inflammation. It also inhibits NF-κB activation, thereby suppressing proinflammatory cytokine production (e.g., IL-6, IL-1, TNF-α) in monocytes/macrophages and T cells, contributing to its immunomodulatory effects.

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