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MASM7

CAT: 0957-E5826-100mgSize: 100 mgDry Ice: NoHazardous: No
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CAT#:0957-E5826-100mgSize:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
920868-45-7
Target
Mitochondrial Metabolism
Applications
Metabolism
Molecular Formula
C22H23N5O2S2
Additionnal Information
MASM7 is an activator of mitofusins that promotes mitochondrial fusion through mitofusins. It increases mitochondrial AR in MEFs in a concentration-dependent manner, with an EC50 value of 75 nM. MASM7 also directly binds to the HR2 domain of MFN2 with a dissociation constant (Kd) of 1.1 μM, effectively activating MFN2 or MFN to induce fusion.

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C03591-01MASM7