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Nigericin

CAT: 0957-E4788-5mgSize: 5 mgDry Ice: NoHazardous: No
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CAT#:0957-E4788-5mgSize:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
28380-24-7
Target
Potassium Channel
Applications
Transmembrane Transporters
Molecular Formula
C40H68O11
Additionnal Information
Nigericin is an antibiotic derived from Streptomyces hygroscopicus that acts as a K+/H+ ionophore, which causes the efflux of potassium from the cell and, thus, influences the mitochondria membrane potential. It also induces pyroptosis in macrophages by activating NLRP3 inflammasome.