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Semustine

CAT: 0957-E4754-1gSize: 1 gDry Ice: NoHazardous: No
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CAT#:0957-E4754-1gSize:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
13909-09-6
Target
DNA alkylator
Applications
DNA Damage/DNA Repair
Molecular Formula
C10H18ClN3O2
Additionnal Information
Semustine is a member of the chloroethyl nitrosourea (CENU) family that induces DNA alkylation at the major groove, forming interstrand cross-links between guanine and cytosine bases (dG-dC) . It exerts antitumor activity by inducing these DNA cross-links and is used as an antineoplastic alkylating agent for treating Lewis lung carcinoma, leukemia, and metastatic brain tumors.

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