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Pyr3

CAT: 0957-E4659-5mgSize: 5 mgDry Ice: NoHazardous: No
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CAT#:0957-E4659-5mgSize:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1160514-60-2
Target
TRP Channel
Applications
Neuronal Signaling
Molecular Formula
C16H11Cl3F3N3O3
Additionnal Information
Pyr3 is a selective and potent inhibitor of transient receptor potential canonical channel 3 (TRPC3) . It inhibits TRPC3-mediated Ca2+ influx in a dose-dependent manner with the IC50 value of 0.7 μM. It holds potential for treating TRPC3-related diseases like cardiac hypertrophy.

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