Products for Research Use Only
RegisterLogin

CVN293

CAT: 0957-E4642-5mgSize: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0957-E4642-5mgSize:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
2815296-08-1
Target
Potassium Channel
Applications
Transmembrane Transporters
Molecular Formula
C14H10FN7O
Additionnal Information
CVN293 is a potent, selective, and brain permeable small-molecule inhibitor of potassium (K+) ion channel KCNK13 with an IC50s of 49 nM and 28 nM for hKCNK13 and mKCNK13, respectively. It also inhibits NOD-like receptor protein 3 (NLRP3) inflammasome-mediated IL-1ß production in LPS-stimulated primary neonatal murine microglia with an IC50 of 24 nM and has potential applications in Alzheimer’s disease research.

Alternative Products

CatalogName
T86109-01CVN293

Popular Products