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Copanlisib dihydrochloride

CAT: 0957-E4605-1gSize: 1 gDry Ice: NoHazardous: No
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CAT#:0957-E4605-1gSize:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1402152-13-9
Synonyms
BAY 80-6946 dihydrochloride
Target
PI3K
Applications
PI3K/Akt/mTOR
Molecular Formula
C23H28N8O4.2ClH
Additionnal Information
Copanlisib dihydrochloride (BAY 80-6946 dihydrochloride) is a selective and potent inhibitor of pan-class I PI3K. It significantly inhibits the catalytic activity of class I PI3K isoforms α, β, γ, and δ with IC50 of 0.5, 3.7, 6.4, and 0.7 nM, respectively. BAY 80-6946 exhibits potent antitumor activity in multiple cell-line–derived and patient-derived xenograft tumor models.

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