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YD23

CAT: 0957-E1985-1gSize: 1 gDry Ice: NoHazardous: No
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CAT#:0957-E1985-1gSize:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2951015-29-3
Target
PROTAC
Applications
Others
Molecular Formula
C38H39FN8O7
Additionnal Information
YD23 is a PROTAC which induces the degradation of SMARCA2. It reduces chromatin accessibility in SMARCA4-deficient cells, affecting gene enhancers related to cell cycle and growth regulation, which leads to the downregulation of several cell cycle genes. It also selectively inhibits the growth of SMARCA4 mutant lung cancer cells in vitro.

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