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BAL-0028

CAT: 0957-E1970-1gSize: 1 gDry Ice: NoHazardous: No
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CAT#:0957-E1970-1gSize:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2842012-69-3
Target
NLRP3
Applications
Immunology & Inflammation
Molecular Formula
C24H22FN3O2
Additionnal Information
BAL-0028 (Compound 3), which belongs to the indazole class is an inhibitor of NLRP3 activation with an IC50 value of 25 nM. BAL-0028 binds tightly to the NACHT domain of NLRP3, with KD values ranging from 104 to 123 nM. BAL-0028 also exhibits anti-inflammatory activity.