Products for Research Use Only

HRO761

CAT: 0957-E1908-1gSize: 1 gDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0957-E1908-1gSize:1 g
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
2869954-34-5
Target
Others
Applications
Others
Molecular Formula
C31H31ClF3N9O5
Additionnal Information
HRO761 is a potent, selective, allosteric inhibitor of Werner syndrome RecQ helicase (WRN) . It binds at the interface of the D1 and D2 helicase domains, locking WRN in an inactive conformation, and demonstrates anti-proliferative effects specifically in microsatellite instability (MSI) cancer cells.