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DB2313

CAT: 0957-E1519-5mgSize: 5 mgDry Ice: NoHazardous: No
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CAT#:0957-E1519-5mgSize:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2170606-74-1
Target
Immunology & Inflammation related
Applications
Immunology & Inflammation
Molecular Formula
C42H41FN8O2
Additionnal Information
DB2313 is a potent inhibitor of the transcription factor PU.1, effectively blocking PU.1-dependent reporter gene transactivation with an IC50 of 5 μM. DB2313 demonstrated significant anti-leukemic activity by inducing apoptosis in acute myeloid leukemia (AML) cells. It also increases survival rates and reduces tumor burden in vivo.

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