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Nesuparib

CAT: 0957-E1425-25mgSize: 25 mgDry Ice: NoHazardous: No
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CAT#:0957-E1425-25mgSize:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2055357-64-5
Synonyms
JPI-547, NOV140201
Target
PARP
Applications
DNA Damage/DNA Repair
Molecular Formula
C23H24N6O
Additionnal Information
Nesuparib (JPI-547, NOV140201) is a potential inhibitor of both PARP and tankyrases, with IC50 of 0.005 μM, 0.001 μM, 0.002 μM, and ND for TNKS1, TNKS2, PARP1, and PARP2, respectively. Nesuparib exhibits anti-tumor activity in BRCA-deficient xenograft models.

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