Products for Research Use Only
RegisterLogin

Deschloroclozapine

CAT: 0957-E1265-1gSize: 1 gDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0957-E1265-1gSize:1 g
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
1977-07-7
Target
AChR
Applications
Neuronal Signaling
Smiles
CN1CCN (CC1) C2=NC3=CC=CC=C3NC4=CC=CC=C24
Molecular Formula
C18H20N4
Additionnal Information
Deschloroclozapine, a metabolite of Clozapine, is a highly potent muscarinic DREADDs (muscarinic Designer Receptors Exclusively Activated by Designer Drugs) agonist, and binds to DREADD receptor subtypes hM3Dq and hM4Di with Ki of 6.3 and 4.2 nM, respectively.
Storage Conditions
3 years -20°C powder

Chemical Information

11-(4-Methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine

structure given in first source

CAS Number1977-07-7
PubChem CID16103
IUPAC Name6-(4-methylpiperazin-1-yl)-11H-benzo[b][1,4]benzodiazepine
Molecular FormulaC18H20N4
Molecular Weight292.4
XLogP2.4
Topological Polar Surface Area30.9
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count1
Heavy Atom Count22
Formal Charge0
Complexity413
SMILES
CN1CCN(CC1)C2=NC3=CC=CC=C3NC4=CC=CC=C42
InChI
InChI=1S/C18H20N4/c1-21-10-12-22(13-11-21)18-14-6-2-3-7-15(14)19-16-8-4-5-9-17(16)20-18/h2-9,19H,10-13H2,1H3
InChIKey
VQHITFFJBFOMBG-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 11-(4-Methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine
CAS: 1977-07-7
CID: 16103
Formula: C18H20N4
MW: 292.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight292.4
XLogP32.4
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count1
Exact Mass292.16879665
Monoisotopic Mass292.16879665
Topological Polar Surface Area30.9 Ų
Heavy Atom Count22
Formal Charge0
Complexity413
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
463180Deschloroclozapine
A20801-5Deschloroclozapine 5mg
HY-42110A-01Deschloroclozapine (dihydrochloride)
GTR19264800-01Deschloroclozapine dihydrochloride
A20801-100Deschloroclozapine 100mg
A20801-50Deschloroclozapine 50mg
A20801-25Deschloroclozapine 25mg
A20801-10Deschloroclozapine 10mg
A20801-10mM-DDeschloroclozapine 10mM * 1mL in DMSO

Popular Products