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DTRIM24

CAT: 0957-E1143-1mgSize: 1 mgDry Ice: NoHazardous: No
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CAT#:0957-E1143-1mgSize:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2170695-14-2
Molecular Formula
C55H68N8O13S2
Additionnal Information
DTRIM 24 is a is a selective bifunctional degrader of TRIM24 protein, with an IC50 of 337.7 nM. By leveraging the VHL (von Hippel–Lindau) E3 ligase, dTRIM24 induces proteasomal degradation of TRIM24 in a manner dependent on binding both TRIM24’s bromodomain and the VHL complex.