ZAP-180013

CAT: 0957-E0437-25mgSize: 25 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0957-E0437-25mgSize:25 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

CAS Number

873080-25-2

Target

Syk

Applications

Protein Tyrosine Kinase

Molecular Formula

C19H17Cl2N3O4S

Additionnal Information

ZAP-180013 is a inhibitor of zeta-chain-associated protein kinase 70 (ZAP-70) with an IC50 of 1.8 μM.

Storage Conditions

3 years -20°C powder

Chemical Information

5-chloro-N-(4-chlorobenzyl)-2-(ethylsulfonyl)-N-(furan-2-ylmethyl)pyrimidine-4-carboxamide

CAS Number	873080-25-2
PubChem CID	2988718
IUPAC Name	5-chloro-N-[(4-chlorophenyl)methyl]-2-ethylsulfonyl-N-(furan-2-ylmethyl)pyrimidine-4-carboxamide
Molecular Formula	C19H17Cl2N3O4S
Molecular Weight	454.3
XLogP	3.3
Topological Polar Surface Area	102
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	7
Heavy Atom Count	29
Formal Charge	0
Complexity	652

SMILES

CCS(=O)(=O)C1=NC=C(C(=N1)C(=O)N(CC2=CC=C(C=C2)Cl)CC3=CC=CO3)Cl

InChI

InChI=1S/C19H17Cl2N3O4S/c1-2-29(26,27)19-22-10-16(21)17(23-19)18(25)24(12-15-4-3-9-28-15)11-13-5-7-14(20)8-6-13/h3-10H,2,11-12H2,1H3

InChIKey

GTWKIPDKVRLUKN-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 873080-25-2

CID: 2988718

Formula: C19H17Cl2N3O4S

MW: 454.3

Interactive 3D Structure

Loading 3D structure...

Computed Properties

Property	Value
Molecular Weight	454.3
XLogP3	3.3
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	7
Exact Mass	453.0316826
Monoisotopic Mass	453.0316826
Topological Polar Surface Area	102 Å²
Heavy Atom Count	29
Formal Charge	0
Complexity	652
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Catalog	Name
F4220-01	Zap-70 Antibody [E5E23]
F0458-01	Zap-70 Rabbit mAb
F4220-100uL	Zap-70 Antibody [E5E23]
F0458-20ul	Zap-70 Rabbit mAb
F4220-100uL*2	Zap-70 Antibody [E5E23]
F0458-100uL*2	Zap-70 Rabbit mAb
F0458-100ul	Zap-70 Rabbit mAb
F4220-20uL	Zap-70 Antibody [E5E23]
F0556-20uL	Phospho-Zap-70 (Tyr319) /Syk (Tyr352) Rabbit mAb
F0556-100uL*2	Phospho-Zap-70 (Tyr319) /Syk (Tyr352) Rabbit mAb

Catalog	Name
BA8376-100	ZAP-180013
6821/10	ZAP 180013
YP-W69334-01	Chicken ZAP (ZAP) ELISA Kit
529765-01	ZAP-70
CST 72310S	ZAP Antibody
abx140043	Tyrosine-Protein Kinase ZAP-70 (ZAP-70) Antibody
20R-2009	Zap 70 antibody
GWB-77D9FB	ZAP-70, Antibody
543869-01	ZAP-70 discontinued