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ASP8497

CAT: 0804-HY-123171Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-123171Size:1 Each
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Description
ASP8497 is a competitive dipeptidyl peptidase IV (DPP-IV) inhibitor that reduces blood glucose levels and increases plasma active GLP-1 and insulin levels without causing hypoglycemia in fasted normal mice. ASP8497 can be utilized for antihyperglycemic research[1].
CAS Number
651055-26-4
UNSPSC
12352005
Target
Dipeptidyl Peptidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/asp8497.html
Smiles
CC1(NCC(N2C[C@@H](F)C[C@H]2C#N)=O)CCN(S(=O)(C)=O)CC1.O=C(O)/C=C/C(O)=O
Molecular Formula
C18H27FN4O7S
Molecular Weight
462.49
References & Citations
[1]Someya Y, et al. Pharmacological profile of ASP8497, a novel, selective, and competitive dipeptidyl peptidase-IV inhibitor, in vitro and in vivo. Naunyn Schmiedebergs Arch Pharmacol. 2008 May;377 (3) :209-17.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported