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[Phe17]-Apelin 17

CAT: 1601-CCP1738-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:1601-CCP1738-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Peptide to [Phe17]-Apelin 17
CAS Number
217082-57-0
Structure Composition
Lys-Phe-Arg-Arg-Gln-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe
Applications
Apelin-17 is an endogenous ligand of the human orphan G protein-coupled receptor APJ, reported to act as a coreceptor of CD4 for human and simian immunodeficiency viruses. Apelin-17 and apelin-13 represent the predominant molecular forms of apelin present in the whole brain, hypothalamus, and plasma. Like apelin-13, apelin-17 exhibited a high activity on extracellular acidification rate and strongly inhibited forskolin-stimulated cAMP production in CHO cells expressing the human or the rat apelin receptor. The peptide might play a crucial role in the maintenance of body fluid homeostasis by counteracting AVP (arginine vasopressin) actions through inhibition of AVP neuron activity and AVP release.
Purity
> 95%
Form
Lyophilized powder
Molecular Formula
C96H156N34O20S
Molecular Weight
2138.59
Storage Conditions
Shipped at 4°C. Store at -20°C for one year.
Light Source
Synthetic

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