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Amylin, Rat

CAT: 1601-CCP1070-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:1601-CCP1070-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Peptide to Amylin, Rat
Structure Composition
H-Lys-Cys-Asn-Thr-Ala-Thr-Cys-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-Arg-Ser-Ser-Asn-Asn-Leu-Gly-Pro-Val-Leu-Pro-Pro-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH2 (Disulfide bridge Cys2-Cys7)
Applications
Endogenous peptide secreted by pancreatic β-cells. Potently activates amylin, calcitonin (EC50 = 0.67 nM), CGRP and adrenomedullin receptors. Potently inhibits insulin-stimulated glucose uptake (IC50 = 12 pM) . Implicated in type II diabetes.
Purity
> 95%
Form
Lyophilized powder
Molecular Formula
C165H261N51O55S2
Molecular Weight
3903.4
Storage Conditions
Shipped at 4°C. Store at -20°C for one year.
Light Source
Synthetic

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