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ZM-323881

CAT: 1106-BML-EI385-0001Size: 1 mgDry Ice: NoHazardous: No
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CAT#:1106-BML-EI385-0001Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
193001-14-8
Product Name Alternative
5- ((7-Benzyloxyquinazolin-4-yl) amino) -4-fluoro-2-methyl phenol
Certification
RUO
Target
VEGFR
Type
Inhibitor
Source
Synthetic.
Stability
As indicated on product label or CoA when stored as recommended. Stable for 1 year as supplied. Stock solutions can be stored at -20°C for up to 3 months.
Purity
≥98% (TLC)
Solubility
Soluble in DMSO (3 mg/ml) .
Molecular Formula
C 22 H 18 FN 3 O 2
Molecular Weight
375.4
Shipping Conditions
Ambient Temperature
Storage Conditions
-20°C
Appearance
White to off-white solid.

Chemical Information

5-((7-(Benzyloxy)quinazolin-4-yl)amino)-4-fluoro-2-methylphenol

ZM 323881 is a member of the class of quinazolines carrying 2-fluoro-4-methyl-5-hydroxyanilino and benzyloxy substituents at positions 4 and 7 respectively. It has a role as a vascular endothelial growth factor receptor antagonist. It is a fluorophenol, an organic cation, an aromatic ether, a member of quinazolines, a halophenol, a substituted aniline, a secondary amino compound, a benzyl ether and a member of monofluorobenzenes. It is a conjugate base of a ZM 323881(1+).

CAS Number193001-14-8
PubChem CID16759369
IUPAC Name4-fluoro-2-methyl-5-[(7-phenylmethoxyquinazolin-4-yl)amino]phenol
Molecular FormulaC22H18FN3O2
Molecular Weight375.4
XLogP5
Topological Polar Surface Area67.3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count5
Heavy Atom Count28
Formal Charge0
Complexity490
SMILES
CC1=CC(=C(C=C1O)NC2=NC=NC3=C2C=CC(=C3)OCC4=CC=CC=C4)F
InChI
InChI=1S/C22H18FN3O2/c1-14-9-18(23)20(11-21(14)27)26-22-17-8-7-16(10-19(17)24-13-25-22)28-12-15-5-3-2-4-6-15/h2-11,13,27H,12H2,1H3,(H,24,25,26)
InChIKey
NVBNDZZLJRYRPD-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 5-((7-(Benzyloxy)quinazolin-4-yl)amino)-4-fluoro-2-methylphenol
CAS: 193001-14-8
CID: 16759369
Formula: C22H18FN3O2
MW: 375.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight375.4
XLogP35
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count5
Exact Mass375.13830499
Monoisotopic Mass375.13830499
Topological Polar Surface Area67.3 Ų
Heavy Atom Count28
Formal Charge0
Complexity490
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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A11954-10ZM 323881 hydrochloride 10mg
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