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Streptozotocin

CAT: 1106-ALX-380-010-5100Size: 5x 100 mgDry Ice: YesHazardous: No
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CAT#:1106-ALX-380-010-5100Size:5x 100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
18883-66-4
Product Name Alternative
Streptozocin, 2-Deoxy-2- (3-methyl-3-nitrosoureido) -D-glucopyranose, STZ
Certification
RUO
Target
O-GlcNAcase
Type
Inhibitor
Source
Isolated from Streptomyces achromogenes .
Stability
As indicated on product label or CoA when stored as recommended. Because solutions of the compound spontaneously give off NO gas at room temperature, we recommend that solutions be made immediately before use.
Purity
≥97% (HPLC)
Solubility
Soluble in 100% ethanol (200 proof at 0.92mg/ml) or water (nH2O at 102.8mg/ml) .
Molecular Formula
C 8 H 15 N 3 O 7
Molecular Weight
265.2
Shipping Conditions
Dry Ice
Storage Conditions
-20°C
Notes
Solutions of Streptozotocin will spontaneously give off NO gas at room temperature. This NO release is slowed, but not completely stopped at -80°C, and the rate of NO release is also impacted by the solvent used (for example, dissolving Streptozotocin in buffers that contain sodium speeds up NO release) . Since it does not seem to be possible to completely stop the NO release when streptozotocin is in solution, and the NO donor function is critical to the majority of experimental applications, we recommend that customers make solutions only immediately before use. Note: since streptozotocin is often used to treat animals, the requirement that solutions be made immediately before use can be overwhelming for some users. Therefore, we generally suggest that the material be initially dissolved in ethanol, aliquoted into single use amounts, and then the alcohol evaporated off to produce dry aliquots. NO loss is minimized by doing this procedure with the material on ice, and carrying it out as quickly as possible. The individual dry aliquots can then be easily dissolved immediately before use.
Appearance
White to pale yellow crystalline solid.
RTECS
LZ5775000

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