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Estrogen receptor α polyclonal antibody

CAT: 1106-ALX-210-201-C050Size: 50 µgDry Ice: NoHazardous: No
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CAT#:1106-ALX-210-201-C050Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Product Name Alternative
ERα
Certification
RUO
UniProt
P03372
Host
Rabbit
Species Reactivity
Human, Rat
Immunogen
Synthetic peptide corresponding to aa 1-21 (M1TMTLHTKASGMALLHQIQGN21) of N-terminal human ERα (estrogen receptor α) . This sequence is completely conserved in rat and mouse ERα and is highly conserved in sheep, pig, dog, bovine and chicken ERα.
Applications
IHC (FS), WB
Purification
Epitope-affinity purified IgG.
Dilution
Immunohistochemistry (frozen sections, 1-5μg/ml) Western Blot (1μg/ml) Suggested dilutions/conditions may not be available for all applications.Optimal conditions must be determined individually for each application.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C
Specificity
Recognizes endogenous ERα.
Formulation
Liquid. In PBS containing 1mg/ml BSA and 0.05% sodium azide.
Applications Notes
Detects a band of ~64kDa by Western blot.
Warranty
This antibody is covered by our Worry-Free Guarantee .
Cross Reactivity Details
Does not cross-react with ERβ.

UniProtKB · P03372

Estrogen receptor

ESR1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P03372
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ESR1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
ER
EC number
—
Processing
—
Secondary accessions
Q13511, Q14276, Q5T5H7, Q6MZQ9, Q9NU51, Q9UDZ7, Q9UIS7
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Molecular function

ActivatorDNA-bindingReceptor

Coding sequence diversity

Alternative promoter usageAlternative splicing

Cellular component

Cell membraneCytoplasmGolgi apparatusMembraneNucleus

Disease

Disease variantOsteoporosis

PTM

GlycoproteinLipoproteinMethylationPalmitatePhosphoproteinUbl conjugation

Ligand

Lipid-bindingMetal-bindingSteroid-bindingZinc

Biological process

TranscriptionTranscription regulation

Domain

TransmembraneZinc-finger

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