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Adenylate cyclase toxin

CAT: 1106-BML-CN150A-0050Size: 50 µgDry Ice: YesHazardous: No
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CAT#:1106-BML-CN150A-0050Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Product Name Alternative
AC toxin
Certification
RUO
UniProt
J7QLC0
Source
Produced in E. coli.
Stability
As indicated on product label or CoA when stored as recommended.
Purity
≥80% (SDS-PAGE)
Molecular Weight
~200 kDa
Shipping Conditions
Dry Ice
Storage Conditions
-20°C
Formulation
Liquid. In 0.05M Tris-HCl and 8M Urea pH 8.0.
Applications Notes
AC toxin is a unique tool for increasing cAMP levels in mammalian cells.

UniProtKB · J7QLC0

Bifunctional hemolysin/adenylate cyclase

CYAA_BORP1 · Bordetella pertussis (strain ATCC 9797 / DSM 5571 / CCUG 30873 / LMG 14455 / NCTC 10739 / 18323)

View on UniProt ↗
Primary accession
J7QLC0
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
cya
Protein existence
1: Evidence at protein level
Organism
Bordetella pertussis (strain ATCC 9797 / DSM 5571 / CCUG 30873 / LMG 14455 / NCTC 10739 / 18323)
Taxonomy ID
568706
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
P15318
Protein keywords

Technical term

3D-structureReference proteome

Ligand

ATP-bindingCalciumNucleotide-binding

Molecular function

Calmodulin-bindingLyaseToxin

Biological process

cAMP biosynthesisCytolysisHemolysisVirulence

Cellular component

Host cell membraneHost membraneMembraneSecreted

PTM

LipoproteinMyristatePalmitate

Domain

RepeatTransmembrane

Disease

Whooping cough

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