STAT3-IN-13

• CAS Number :

  2248552-86-3

• SKU :

  C18350-5mg

• Target :

  STAT

• Applications :

  Apoptosis

• Smiles :

  N#CC1=C (SC2=C1CCN (C2) C (NC3=CC=C (C=C3) OC) =O) NC (C (C=N4) =CN4C) =O

• Molecular Formula :

  C21H20N6O3S

• Additionnal Information :

  STAT3-IN-13 (compound 6f) is a STAT3 inhibitor. It exhibits anti-proliferative activity and binds to the STAT3 SH2 domain with a KD of 0.46 μM. This compound inhibits STAT3 Y705 phosphorylation and downstream target gene expression. In vitro studies show STAT3-IN-13 induces apoptosis, while in vivo experiments demonstrate its ability to suppress tumor growth and metastasis. STAT3-IN-13 has potential applications in cancer research.

• Storage Conditions :

  3 years-20°C powder 2 years-80°C in solvent