USP5-IN-1

CAT: 1568-C18337-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:1568-C18337-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2851040-81-6
SKU
C18337-5mg
Smiles
O=S (C1=CC=C (C (NCC (O) =O) =O) N=C1) (N2CCC (C3=CC=C (Cl) C=C3) CC2) =O
Molecular Formula
C19H20ClN3O5S
Additionnal Information
USP5-IN-1 (compound 64) is a selective competitive inhibitor of USP5 zinc finger ubiquitin binding domain (ZnF-UBD) with a Kd of 2.8 μM. It competitively blocks ubiquitin binding to the ZnF-UBD domain, suppressing USP5 catalytic activity and ubiquitin chain hydrolysis, with potential applications as a chemical probe and therapeutic agent in USP5-related cancers.

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