KG-501

• CAS Number :

  18228-17-6

• Synonyms :

  2-naphthol-AS-E-phosphate

• SKU :

  C18178-25mg

• Target :

  Epigenetic Reader Domain

• Applications :

  Epigenetics

• Smiles :

  C1=CC=C2C=C (C (=CC2=C1) C (=O) NC3=CC=C (C=C3) Cl) OP (=O) (O) O

• Molecular Formula :

  C17H13ClNO5P

• Additionnal Information :

  KG-501 is a cAMP response element-binding protein (CREB) inhibitor that disrupts CREB-dependent transcription (Ki = 10 μM) and CREB:CBP interaction (Ki = 50 μM) . It also disrupts phospho (Ser-133) CREB binding to KIX with a Ki of ≈90 μM, using concentrations of CREB that were within the linear range of the binding assay.

• Storage Conditions :

  3 years -20°C powder