WAY-600

• CAS Number :

  1062159-35-6

• SKU :

  C17004-10mg

• Target :

  MTOR

• Applications :

  PI3K/Akt/mTOR

• Smiles :

  C1CN (CCC1N2C3=C (C=N2) C (=NC (=N3) C4=CC5=C (C=C4) NC=C5) N6CCOCC6) CC7=CN=CC=C7

• Molecular Formula :

  C28H30N8O

• Additionnal Information :

  WAY-600 is a potent, ATP-competitive and selective inhibitor of mTOR with IC50 of 9 nM; blocks mTORC1/P-S6K (T389) and mTORC2/P-AKT (S473) but not P-AKT (T308) ; selective for mTOR than PI3Kα (>100-fold) and PI3Kγ (>500-fold) .

• Storage Conditions :

  2 years -80 in solvent