CHIR-124

• CAS Number :

  405168-58-3

• SKU :

  C16998-2mg

• Target :

  Chk

• Applications :

  Cell Cycle

• Smiles :

  C1CN2CCC1C (C2) NC3=C (C (=O) NC4=C3C=C (C=C4) Cl) C5=NC6=CC=CC=C6N5

• Molecular Formula :

  C23H22ClN5O

• Additionnal Information :

  CHIR-124 is a novel and potent Chk1 inhibitor with IC50 of 0.3 nM in a cell-free assay. It shows 2,000-fold selectivity against Chk2, 500- to 5,000-fold less activity against CDK2/4 and Cdc2.

• Storage Conditions :

  2 years -80 in solvent