OSI-027

CAT: 1568-C16958Size: 10 mgDry Ice: YesHazardous: No
CAT#:1568-C16958Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
936890-98-1
Synonyms
ASP4786, CERC 006, AEVI-006
SKU
C16958-10mg
Target
MTOR
Applications
PI3K/Akt/mTOR
Smiles
COC1=CC=CC2=C1NC (=C2) C3=C4C (=NC=NN4C (=N3) C5CCC (CC5) C (=O) O) N
Molecular Formula
C21H22N6O3
Additionnal Information
OSI-027 (ASP4786, CERC 006, AEVI-006) is a selective and potent dual inhibitor of mTORC1 and mTORC2 with IC50 of 22 nM and 65 nM in cell-free assays, and more than 100-fold selectivity observed for mTOR than PI3Kα, PI3Kβ, PI3Kγ or DNA-PK. OSI-027 induces autophagy in cancer cells.
Storage Conditions
2 years -80 in solvent

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