Products for Research Use Only
RegisterLogin

Rigosertib (ON-01910)

CAT: 1568-C16269Size: 10 mgDry Ice: YesHazardous: No
Product image 1
1 / 1
CAT#:1568-C16269Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
1225497-78-8
SKU
C16269-10mg
Target
PLK
Applications
Cell Cycle
Smiles
COC1=C (C=C (C=C1) CS (=O) (=O) C=CC2=C (C=C (C=C2OC) OC) OC) NCC (=O) [O-].[Na+]
Molecular Formula
C21H24NNaO8S
Additionnal Information
Rigosertib (ON-01910) is a non-ATP-competitive inhibitor of PLK1 with IC50 of 9 nM in a cell-free assay. It shows 30-fold greater selectivity against Plk2 and no activity to Plk3. Rigosertib inhibits PI3K/Akt pathway and activates oxidative stress signals. Rigosertib induces apoptosis in various cancer cells. Phase 3.
Storage Conditions
2 years -80 in solvent

Related Products

CatalogName
C03806-5mgRigosertib
C03806Rigosertib

Alternative Products

CatalogName
MBS130460-01Rigosertib (ON-01910)
MBS385857-01ON-01910 (rigosertib)
A10673-5(E/Z) -Rigosertib sodium ((E/Z) -ON-01910 sodium) 5mg
A10673-100(E/Z) -Rigosertib sodium ((E/Z) -ON-01910 sodium) 100mg
A10673-10(E/Z) -Rigosertib sodium ((E/Z) -ON-01910 sodium) 10mg
A10673-50(E/Z) -Rigosertib sodium ((E/Z) -ON-01910 sodium) 50mg
A10673-25(E/Z) -Rigosertib sodium ((E/Z) -ON-01910 sodium) 25mg
A10673-2(E/Z) -Rigosertib sodium ((E/Z) -ON-01910 sodium) 2mg
A10673-10mM-D(E/Z) -Rigosertib sodium ((E/Z) -ON-01910 sodium) 10mM * 1mL in DMSO
E1KS1362ON-01910

Popular Products