BI-3406

• CAS Number :

  2230836-55-0

• SKU :

  C13779-5mg

• Target :

  Ras

• Applications :

  Apoptosis

• Smiles :

  CC1=NC2=CC (=C (C=C2C (=N1) NC (C) C3=CC (=CC (=C3) N) C (F) (F) F) OC4CCOC4) OC

• Molecular Formula :

  C23H25F3N4O3

• Additionnal Information :

  BI-3406 (compound I-13) is a potent, selective and orally active inhibitor of the interaction between KRAS and Son of Sevenless 1 (SOS1) with IC50 of 5 nM. BI-3406 reduces the formation of GTP-loaded KRAS, and inhibits MAPK pathway signaling. BI-3406 exhibits anti-tumor activities.

• Storage Conditions :

  3 years -20°C powder