SR-4835

• CAS Number :

  2387704-62-1

• SKU :

  C13758-5mg

• Target :

  CDK

• Applications :

  Cell Cycle

• Smiles :

  CN1C=C (C=N1) N2C=NC3=C (N=C (N=C32) N4CCOCC4) NCC5=NC6=CC (=C (C=C6N5) Cl) Cl

• Molecular Formula :

  C21H20Cl2N10O

• Additionnal Information :

  SR-4835 is a highly selective dual inhibitor of CDK12 and CDK13 with IC50 of 99 nM and Kd of 98 nM for CDK12 and IC50 of 4.9 nM for CDK13. SR-4835 disables triple-negative breast cancer (TNBC) cells. SR-4835 promotes synergy with DNA-damaging chemotherapy and PARP inhibitors.

• Storage Conditions :

  3 years -20°C powder