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TAS0728

CAT: 1568-C13705-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:1568-C13705-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2088323-16-2
Synonyms
TPC 107
SKU
C13705-5mg
Target
HER2
Applications
Protein Tyrosine Kinase
Smiles
CC1=C (C=CC (=C1C) NC (=O) C2=NN (C3=NC=NC (=C23) N) C4CCCN (C4) C (=O) C=C) CC (=O) N (C) C
Molecular Formula
C26H32N8O3
Additionnal Information
TAS0728 (TPC 107) is a potent, selective, orally active, irreversible and covalent-binding inhibitor of HER2 (human epidermal growth factor receptor 2) with IC50 of 13 nM. TAS0728 inihibits BMX, HER4, BLK, EGFR, JAK3, SLK, LOK and human HER2 with IC50 of 4.9 nM, 8.5 nM, 31 nM, 65 nM, 33 nM, 25 nM, 86 nM and 36 nM, respectively. TAS0728 shows antitumor activity.
Storage Conditions
3 years -20°C powder

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HY-111553-01TAS0728
A19382-200TAS0728 200mg
A19382-5TAS0728 5mg
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A19382-50TAS0728 50mg
A19382-100TAS0728 100mg
A19382-25TAS0728 25mg
A19382-10TAS0728 10mg
A19382-1TAS0728 1mg
A19382-10mM-DTAS0728 10mM * 1mL in DMSO

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