V-9302

CAT: 1568-C13694-01Size: 5 mgDry Ice: NoHazardous: No

CAT#:1568-C13694-01Size:5 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

1855871-76-9

SKU

C13694-5mg

Target

Amino acid transporter

Applications

Transmembrane Transporters

Smiles

CC1=CC (=CC=C1) COC2=CC=CC=C2CN (CCC (C (=O) O) N) CC3=CC=CC=C3OCC4=CC=CC (=C4) C

Molecular Formula

C34H38N2O4

Additionnal Information

V-9302 is a competitive small molecule antagonist of transmembrane glutamine flux, that selectively and potently targets the amino acid transporter ASCT2 (SLC1A5) with an IC50 value of 9.6 μM for inhibition of glutamine uptake in HEK-293 cells. V-9302 blocks Sodium-neutral AA transporter 2 (SNAT2, SLC38A2) and the large neutral AA transporter 1 (LAT1, SLC7A5) as observed in 143B osteosarcoma cells, HCC1806 breast cancer cells and Xenopus laevis oocytes. Dilution of PBS may cause a clear aqueous solution to turn into a uniform suspension.

Storage Conditions

3 years -20°C powder

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V-9302

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