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PF-06840003

CAT: 1568-C13566-01Size: 5 mgDry Ice: YesHazardous: No
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CAT#:1568-C13566-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
198474-05-4
Synonyms
EOS200271
SKU
C13566-5mg
Target
IDO/TDO
Applications
Metabolism
Smiles
C1C (C (=O) NC1=O) C2=CNC3=C2C=C (C=C3) F
Molecular Formula
C12H9FN2O2
Additionnal Information
PF-06840003 (EOS200271) is a highly selective orally bioavailable IDO-1 inhibitor. Although it has moderate hIDO1 enzyme inhibition (IC50 0.41 μM), it is a highly efficient compound (LE 0.53, LipE 5.1), driven by its tight packing within the enzyme, as well as the high density of hydrogen bonds it forms with hIDO-1 despite its small size.
Storage Conditions
2 years -80 in solvent

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