Alrizomadlin
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Alrizomadlin
CAS Number :
1818393-16-6Synonyms :
APG-115, AA-115SKU :
C13484-5mgTarget :
MDM2/MDMXApplications :
ApoptosisMolecular Formula :
C34H38Cl2FN3O4Additionnal Information :
Alrizomadlin (APG-115, AA-115) is a highly potent and efficacious inhibitor of MDM2 and binds to MDM2 with IC50 of 3.8 nM. It exhibits potent antiproliferative and apoptogenic activities and also significantly reduces tumor burden and prolonged survival in AML xenograft models.

