RegisterLogin

Mivebresib (ABBV-075)

CAT: 1568-C13393-01Size: 5 mgDry Ice: YesHazardous: No
5 mgSelected
PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
CAS Number
1445993-26-9
SKU
C13393-5mg
Target
Epigenetic Reader Domain
Applications
Epigenetics
Smiles
CCS (=O) (=O) NC1=CC (=C (C=C1) OC2=C (C=C (C=C2) F) F) C3=CN (C (=O) C4=C3C=CN4) C
Molecular Formula
C22H19F2N3O4S
Additionnal Information
Mivebresib (ABBV-075) is a novel BET family bromodomain inhibitor. It binds bromodomains of BRD2/4/T with similar affinities (Ki of 1-2.2 nM) and highly selective for 18 bromodomain proteins tested (Kd > 1 μM; more than 600-fold selectivity vs. BRD4), but exhibits roughly 10-fold weaker potency towards BRD3 (Ki of 12.2 nM) and has moderate activity towards CREBBP (Kd = 87 μM; 54-fold selectivity vs. BRD4) . Mivebresib (ABBV-075) efficiently triggers apoptosis in various tumor cell.
Storage Conditions
2 years -80 in solvent

Related Products

CatalogName
C13617-01ABBV-744
C04958ABBV-969 Payload
C13476-01Galicaftor (ABBV-2222)
C01543-01Osunprotafib (ABBV-CLS-484)
C16979-01MK-0752
C08756-01MK-0752

Alternative Products

CatalogName
MBS3842201-01Mivebresib (ABBV-075)
MBS131345Mivebresib (ABBV075, ABBV-075, ABBV 075)
A17226-2Mivebresib (ABBV-075) 2mg
A17226-1Mivebresib (ABBV-075) 1mg
A17226-5Mivebresib (ABBV-075) 5mg
A17226-10Mivebresib (ABBV-075) 10mg
A17226-50Mivebresib (ABBV-075) 50mg
A17226-25Mivebresib (ABBV-075) 25mg
A17226-100Mivebresib (ABBV-075) 100mg
A17226-10mM-DMivebresib (ABBV-075) 10mM * 1mL in DMSO

Popular Products