BMS-986142

• CAS Number :

  1643368-58-4

• SKU :

  C13382-1mg

• Target :

  BTK

• Applications :

  Protein Tyrosine Kinase

• Smiles :

  CC1=C (C=CC=C1N2C (=O) C3=C (C (=CC=C3) F) N (C2=O) C) C4=C (C=C (C5=C4C6=C (N5) CC (CC6) C (C) (C) O) C (=O) N) F

• Molecular Formula :

  C32H30F2N4O4

• Additionnal Information :

  BMS-986142 is a potent and highly selective reversible small molecule inhibitor of BTK with an IC50 of 0.5 nM. In a panel of 384 kinases, only five kinases were inhibited by BMS-986142 with less than 100-fold selectivity for BTK (TEC, ITK, BLK, TXK and BMX) .

• Storage Conditions :

  3 years -20°C powder