NMS-P118

• CAS Number :

  1262417-51-5

• SKU :

  C13369-5mg

• Target :

  PARP

• Applications :

  DNA Damage/DNA Repair

• Smiles :

  C1CC (CCC1N2CCC (CC2) N3CC4=C (C3=O) C (=CC (=C4) F) C (=O) N) (F) F

• Molecular Formula :

  C20H24F3N3O2

• Additionnal Information :

  NMS-P118 is a potent, orally available, and highly selective PARP-1 inhibitor endowed with excellent ADME and pharmacokinetic profiles, showing 150-fold selectivity for PARP-1 over PARP-2 (Kd 0.009 μM vs 1.39 μM, respectively) .

• Storage Conditions :

  2 years -80 in solvent