GNF-7

• CAS Number :

  839706-07-9

• SKU :

  C13213-5mg

• Target :

  Bcr-Abl

• Applications :

  Protein Tyrosine Kinase

• Smiles :

  CC1=C (C=C (C=C1) NC (=O) C2=CC (=CC=C2) C (F) (F) F) N3CC4=CN=C (N=C4N (C3=O) C) NC5=CN=C (C=C5) C

• Molecular Formula :

  C28H24F3N7O2

• Additionnal Information :

  GNF-7 is a potent type-II kinase Bcr-Abl inhibitor with IC50 of <5 nM, 61 nM, 122 nM, 136 nM, and 133 nM for M351T, T315I, E255 V, G250E, and c-Abl, respectively.

• Storage Conditions :

  2 years -80 in solvent