KU-0060648

• CAS Number :

  881375-00-4

• SKU :

  C13151-2mg

• Target :

  DNA-PK

• Applications :

  PI3K/Akt/mTOR

• Smiles :

  CCN1CCN (CC1) CC (=O) NC2=C3C4=CC=CC=C4SC3=C (C=C2) C5=CC=CC6=C5OC (=CC6=O) N7CCOCC7

• Molecular Formula :

  C33H34N4O4S

• Additionnal Information :

  KU-0060648 is a dual inhibitor of DNA-PK and PI3Kα, PI3Kβ, PI3Kδ with IC50 of 8.6 nM and 4 nM, 0.5 nM, 0.1 nM respectively, less inhibition of PI3Kγ with IC50 of 0.59 μM.

• Storage Conditions :

  2 years -80 in solvent