GDC-0349

• CAS Number :

  1207360-89-1

• Synonyms :

  RG-7603

• SKU :

  C13146-5mg

• Target :

  MTOR

• Applications :

  PI3K/Akt/mTOR

• Smiles :

  CCNC (=O) NC1=CC=C (C=C1) C2=NC3=C (CCN (C3) C4COC4) C (=N2) N5CCOCC5C

• Molecular Formula :

  C24H32N6O3

• Additionnal Information :

  GDC-0349 (RG-7603) is a potent and selective ATP-competitive inhibitor of mTOR with Ki of 3.8 nM, 790-fold inhibitory effect against PI3Kα and other 266 kinases. Phase 1.

• Storage Conditions :

  2 years -80 in solvent