MI-503

• CAS Number :

  1857417-13-0

• SKU :

  C12973-2mg

• Target :

  Histone Methyltransferase

• Applications :

  Epigenetics

• Smiles :

  CC1=C (C=CC2=C1C=C (N2CC3=CNN=C3) C#N) CN4CCC (CC4) NC5=C6C=C (SC6=NC=N5) CC (F) (F) F

• Molecular Formula :

  C28H27F3N8S

• Additionnal Information :

  MI-503 is a potent and selective Menin-MLL inhibitor with IC50 of 14.7 nM. It shows pronounced growth suppressive activity in a panel of human MLL leukemia cell lines (GI50 at 250 nM-570 nM range), but only a minimal effect in human leukemia cell lines without MLL translocations.

• Storage Conditions :

  2 years -80 in solvent