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SCR7

CAT: 1568-C12912-04Size: 100 mgDry Ice: YesHazardous: No
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CAT#:1568-C12912-04Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
14892-97-8
SKU
C12912-5mg
Target
DNA/RNA Synthesis
Applications
Cell Cycle
Smiles
C1=CC=C (C=C1) C2=NC3=C (NC (=S) NC3=O) N=C2C4=CC=CC=C4
Molecular Formula
C18H12N4OS
Additionnal Information
SCR7 is a specific DNA Ligase IV inhibitor, which blocks nonhomologous end-joining (NHEJ) . It increases the efficiency of HDR-mediated genome editing up to 19-fold using CRISPR/Cas9 in mammalian cells and mouse embryos.
Storage Conditions
2 years -80 in solvent

Chemical Information

Oprea1_571617
CAS Number14892-97-8
PubChem CID10688007
IUPAC Name6,7-diphenyl-2-sulfanylidene-1H-pteridin-4-one
Molecular FormulaC18H12N4OS
Molecular Weight332.4
XLogP2.9
Topological Polar Surface Area99
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count2
Heavy Atom Count24
Formal Charge0
Complexity487
SMILES
C1=CC=C(C=C1)C2=NC3=C(NC(=S)NC3=O)N=C2C4=CC=CC=C4
InChI
InChI=1S/C18H12N4OS/c23-17-15-16(21-18(24)22-17)20-14(12-9-5-2-6-10-12)13(19-15)11-7-3-1-4-8-11/h1-10H,(H2,20,21,22,23,24)
InChIKey
GSRTWXVBHGOUBU-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Oprea1_571617
CAS: 14892-97-8
CID: 10688007
Formula: C18H12N4OS
MW: 332.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight332.4
XLogP32.9
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count2
Exact Mass332.07318219
Monoisotopic Mass332.07318219
Topological Polar Surface Area99 Ų
Heavy Atom Count24
Formal Charge0
Complexity487
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
406600SCR7
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A15447-25SCR7 25mg

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