ML141

CAT: 1568-C12872-01Size: 5 mgDry Ice: YesHazardous: No
CAT#:1568-C12872-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
71203-35-5
Synonyms
CID-2950007
SKU
C12872-5mg
Target
Rho
Applications
Cell Cycle
Smiles
COC1=CC=C (C=C1) C2CC (=NN2C3=CC=C (C=C3) S (=O) (=O) N) C4=CC=CC=C4
Molecular Formula
C22H21N3O3S
Additionnal Information
ML141 (CID-2950007) is demonstrated to be a potent, selective and reversible non-competitive inhibitor of Cdc42 GTPase suitable for in vitro assays, with IC50 of 200 nM and selectivity against other members of the Rho family of GTPases (Rac1, Rab2, Rab7) . ML141 is associated with an increase in p38 activation and may induce p38-dependent apoptosis/senescence. ML141 also protects neuroblastoma cells from metformin-induced apoptosis.
Storage Conditions
2 years -80 in solvent

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Alternative Products

CatalogName
HY-12755-01ML141
MBS130831-01ML141(CID-2950007)
SC6565-5mgML141 (Rho inhibitor)
bs-60134C-01ML141 --- Cdc42 GTPase Inhibitor
217263Cdc42/Rac1 GTPase Inhibitor, ML141 (MLS00693334, CID2950007, (±) -4- (4,5-Dihydro-5- (4-methoxyphenyl) -3-phenyl-1H-pyrazol-1-yl) -benzenesulfonamide, (±) -4- (5- (4-Methoxyphenyl) -3-phenyl-4,5-dihydro-1H-pyrazol-1-yl) ) -benzenesulfonamide, CDC42 GTPase Inhibitor II, CDC42 Inhibitor II, Rac1 Inhibitor V, Rac1 GTPase Inhibitor II)

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