CGP 57380

• CAS Number :

  522629-08-9

• SKU :

  C12673-10mg

• Target :

  MNK

• Applications :

  MAPK

• Smiles :

  C1=CC (=CC=C1NC2=C3C (=NC=NC3=NN2) N) F

• Molecular Formula :

  C11H9FN6

• Additionnal Information :

  CGP 57380 is a potent MNK1 inhibitor with IC50 of 2.2 μM, exhibiting no inhibitory activity on p38, JNK1, ERK1 and -2, PKC, or c-Src-like kinases. CGP 57380 upregulates β-catenin and potentiates radiation-induced apoptosis.

• Storage Conditions :

  2 years -80 in solvent