AMG-517

• CAS Number :

  659730-32-2

• SKU :

  C12454-5mg

• Target :

  TRP Channel

• Applications :

  Neuronal Signaling

• Smiles :

  CC (=O) NC1=NC2=C (C=CC=C2S1) OC3=NC=NC (=C3) C4=CC=C (C=C4) C (F) (F) F

• Molecular Formula :

  C20H13F3N4O2S

• Additionnal Information :

  AMG 517 is a potent and selective TRPV1 antagonist, and antagonizes capsaicin, proton, and heat activation of TRPV1 with IC50 of 0.76 nM, 0.62 nM and 1.3 nM, respectively.

• Storage Conditions :

  2 years -80 in solvent