MD-224

• CAS Number :

  2136247-12-4

• SKU :

  C12303-5mg

• Target :

  MDM2/MDMX

• Applications :

  Apoptosis

• Molecular Formula :

  C48H43Cl2FN6O6

• Additionnal Information :

  MD-224 is a highly potent and effective degrader of the Human murine double minute 2 (MDM2) protein, the main cellular inhibitor of the tumor suppressor p53. It strongly inhibits cell growth in leukemia cell lines with wild-type p53 and induces complete and lasting tumor regression in the RS4;11 xenograft tumor model.