RU.521

• CAS Number :

  2262452-06-0

• Synonyms :

  RU320521

• SKU :

  C12260-5mg

• Target :

  CGAS

• Applications :

  Autophagy

• Smiles :

  CC1=C (C (=O) N (N1) C2=NC3=C (N2) C=CC (=C3Cl) Cl) C4C5=CC=CC=C5C (=O) O4

• Molecular Formula :

  C19H12Cl2N4O3

• Additionnal Information :

  RU.521 (RU320521) is an active, potent and selective inhibitor of cyclic GMP-AMP synthase (cGAS) that inhibits the cGAS-mediated signaling with IC50 of 700 nM. RU.521 binds to the cGAS/dsDNA complex with Kd of 36.2 nM.

• Storage Conditions :

  3 years -20°C powder