SAR7334

CAT: 1568-C12076-02Size: 25 mgDry Ice: NoHazardous: No

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CAT#:1568-C12076-02Size:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

1333210-07-3

SKU

C12076-5mg

Target

TRP Channel

Applications

Neuronal Signaling

Smiles

C1CC (CN (C1) C2CC3=CC=CC=C3C2OC4=C (C=C (C=C4) C#N) Cl) N

Molecular Formula

C21H22ClN3O

Additionnal Information

SAR7334 is a novel, highly potent and bioavailable inhibitor of TRPC6 channels.SAR7334 blocks TRPC6 currents with an IC50 of 7.9 nM in patch-clamp experiment.

Storage Conditions

3 years -20°C powder

Chemical Information

Sar7334

inhibits TRPC6 channels; structure in first source

CAS Number	1333210-07-3
PubChem CID	53378752
IUPAC Name	4-[[(1R,2R)-2-[(3R)-3-aminopiperidin-1-yl]-2,3-dihydro-1H-inden-1-yl]oxy]-3-chlorobenzonitrile
Molecular Formula	C21H22ClN3O
Molecular Weight	367.9
XLogP	3.5
Topological Polar Surface Area	62.3
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	3
Heavy Atom Count	26
Formal Charge	0
Complexity	535

SMILES

C1C[C@H](CN(C1)[C@@H]2CC3=CC=CC=C3[C@H]2OC4=C(C=C(C=C4)C#N)Cl)N

InChI

InChI=1S/C21H22ClN3O/c22-18-10-14(12-23)7-8-20(18)26-21-17-6-2-1-4-15(17)11-19(21)25-9-3-5-16(24)13-25/h1-2,4,6-8,10,16,19,21H,3,5,9,11,13,24H2/t16-,19-,21-/m1/s1

InChIKey

RLKRLNQEXBPQGQ-OZOXKJRCSA-N

Chemical Structure

2D Structure

CAS: 1333210-07-3

CID: 53378752

Formula: C21H22ClN3O

MW: 367.9

Interactive 3D Structure

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View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	367.9
XLogP3	3.5
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	3
Exact Mass	367.1451400
Monoisotopic Mass	367.1451400
Topological Polar Surface Area	62.3 Å²
Heavy Atom Count	26
Formal Charge	0
Complexity	535
Isotope Atom Count	0
Defined Atom Stereocenter Count	3
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Alternative Products

Catalog	Name
M23484-01	SAR7334
A20836-200	SAR7334 200mg
A20836-100	SAR7334 100mg
T12849L-01	SAR7334 hydrochloride
HY-15699A-01	SAR7334 (hydrochloride)
A20836-1	SAR7334 1mg
A20836-50	SAR7334 50mg
A20836-25	SAR7334 25mg
A20836-10	SAR7334 10mg
A20836-5	SAR7334 5mg

SAR7334

Chemical Information

Alternative Products

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