APY29

• CAS Number :

  1216665-49-4

• SKU :

  C12065-5mg

• Target :

  IRE1

• Applications :

  ER stress & UPR

• Smiles :

  C1CC1C2=CC (=NN2) NC3=NC (=NC=C3) NC4=CC5=C (C=C4) N=CN5

• Molecular Formula :

  C17H16N8

• Additionnal Information :

  APY29 is a type I kinase inhibitor of IRE1α that binds to the ATP-binding site on IRE1α and inhibits its autophosphorylation (IC50 = 280 nM) and enhances its RNase function (EC50 = 460 nM) .

• Storage Conditions :

  3 years -20°C powder